ASPIRATION OF BONE MARROW IN LABORATORY ANIMALS
نویسندگان
چکیده
منابع مشابه
Aspiration of bone marrow in laboratory animals.
By R. DOROTHY SUNDBERG, PH.D., AND RUTH E. HODGSON, M.S. I NTEREST in obtaining specimens of bone marrow comparable to those aspirated from the human sternum, ilium, or spinous process caused us to devise a technic which we feel is both simple and reliable. Many similar technics have been described, but most of them have not attained wide usage because they have required minor surgical operatio...
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Background: Bone marrow is the site of many malignant disorders and it is one of the common places for solid tumors to metastasize. Examination of the bone marrow aspirate and biopsy is a routine procedure performed for assessment of various conditions such as cytopenias, hematologic neoplasms, nonmalignant disorders and metastatic neoplasms. Methods: The patients were referred to the Hema...
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Bone marrow aspiration biopsies are carried out principally to permit cytological assessment but also for immunophenotypic, cytogenetic, molecular genetic, and other specialised investigations. Often, a trephine biopsy is carried out as part of the same procedure. Bone marrow aspirations should be carried out by trained individuals who are aware of the indications, contraindications, and hazard...
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Serial sampling of the cellular composition of bone marrow (BM) is a routine procedure critical to clinical hematology. This protocol describes a detailed step-by-step technical procedure for an analogous procedure in live mice which allows for serial characterization of cells present in the BM. This procedure facilitates studies aimed to detect the presence of exogenously administered cells wi...
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Background & objective: Introduction: First detection of any solid tumour as metastatic deposits in bone marrow directs clinicians to start searching for the primary tumour. Detection of bone marrow metastasis determines the stage of the malignancy, prognosis, mode of treatment, chemotherapeutic response and follow-up in case of relapse. The aim of the current...
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ژورنال
عنوان ژورنال: Blood
سال: 1949
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v4.5.557.557